The R package PEARL.installeR provides a way to install FOCUS PEARL in a standardised way on Linux/Unix systems for use with wine. Except that I did not get it to work on my Debian stable with the wine version 1.8.6 available from the backports repository. If you succeed in running Pearlmodel.exe under Linux using wine, I would appreciate a note.
If you (re)install this package, you will have to (re)install PEARL afterwards.
Please refer to the reference.